Tissue Engineering and Genome Engineering

Tissue Engineering can be defined as use of living cells, material and engineering methods, and use of biochemical factors and physicochemical factors, to improve or replace the biological tissues. The main aim of the tissue engineering is to assemble functional constructs that restore, maintain, or improve damaged tissues or whole organs. This field mainly focuses on cures instead of treatments for complex diseases or chronic diseases.  Genome Engineering can be defined as use of engineering methods to modify or to replace the genetic information of the genome of a living organism. This field have many application in fields like human health, agriculture biotechnology( to produce genetically modified crops and plants), in the production of  therapeutic proteins, in production of genetically modified organisms(transgenic sheep, pig, mouse etc),in applied biological research.
  • Transcriptional and epigenetic control in stem cells
  • Plasticity of epithelial, cancer and stem cells
  • Parallels between normal tissue repair response and oncogenesis
  • Targeting the changing tumor microenvironment for anti-cancer therapies
  • Precision genome engineering
  • Research applications of genome & epigenome engineering
  • Novel technologies and therapeutic application of genome engineering

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